• 负责人为中心
  • 宁波大学附属第一医院肝病实验室主任
    • 2021/2022年度德国肝脏研究协会(GASL)主席
    • 德国LiSyM Cancer项目负责人
    • 海德堡大学曼海姆医学院教授
    • ResearchGate评分6.777,H指数为61,文章总引用次数达到14,121次。

      发表论文300余篇,其成果涵盖 Hepatology, GUT, Gastroenterology, Journal of Hepatology, Nature Reviews Gastroenterology & Hepatology, PNAS, Nature Metabolism, Nature Communications, Cell Reports, Science Translational Medicine, Science Signaling 和 Oncogene 等。

    近年发表的主要文章

    1. Link F, Li Y, Zhao J, Munker S, Fan W, Nwosu ZC, Yao Y, Wang S, Huang C, Liebe R, Hammad S, Liu H, Shao C, Gao C, Sun B, Török NJ, Ding H, Ebert MP, Weng H, Ten Dijke P, Drasdo D, Dooley S, Wang S. ECM1 attenuates hepatic fibrosis by interfering with mediators of latent TGF-β1 activation. Gut. 2024 Oct 24:gutjnl-2024-333213.

    2. Wang S, Link F, Han M, Chaudhary R, Asimakopoulos A, Liebe R, Yao Y, Hammad S, Dropmann A, Krizanac M, Rubie C, Feiner LK, Glanemann M, Ebert MPA, Weiskirchen R, Henis YI, Ehrlich M, Dooley S. The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC Activation. Cell Mol Gastroenterol Hepatol. 2024;17(4):567-587.

    3. Tao L, Yang G, Sun T, Jie Tao, Zhu C, Yu H, Cheng Y, Yang Z, Xu M, Jiang Y, Zhang W, Wang Z, Ma W, Wu L, Xue D, Wang D, Yang W, Zhao Y, Horsefield S, Kobe B, Zhang Z, Tang Z, Li Q, Zhai Q, Dooley S, Seki E, Liu P, Xu J, Chen H, Liu C. Capsaicin receptor TRPV1 maintains quiescence of hepatic stellate cells in the liver via recruitment of SARM1. J Hepatol. 2023;78(4):805-819.

    4. Feng R, Kan K, Sticht C, Li Y, Wang S, Liu H, Shao C, Munker S, Niess H, Wang S, Meyer C, Liebe R, Ebert MP, Dooley S, Ding H, Weng H. A hierarchical regulatory network ensures stable albumin transcription under various pathophysiological conditions. Hepatology. 2022;76:1673-1689.

    5. Wang S, Feng R, Wang SS, Liu H, Shao C, Li Y, Link F, Munker S, Liebe R, Meyer C, Burgermeister E, Ebert M, Dooley S, Ding H, Weng H. FOXA2 prevents hyperbilirubinaemia in acute liver failure by maintaining apical MRP2 expression. Gut. 2022;72:549-559.

    6. Li Y, Fan W, Link F, Wang S, Dooley S. Transforming Growth Factor β latency: A mechanism of cytokine storage and signaling regulation in liver homeostasis and disease. JHEP Rep. 2021;4:100397.

    7. Lin T, Wang S, Munker S, Jung K, Macías-Rodríguez RU, Ruiz-Margáin A, Schierwagen R, Liu H, Shao C, Fan C, Feng R, Yuan X, Wang S, Wandrer F, Meyer C, Wimmer R, Liebe R, Kroll J, Zhang L, Schiergens T, Ten Dijke P, Teufel A, Marx A, Mertens PR, Wang H, Pa Ebert M, Bantel H, De Toni E, Trebicka J, Dooley S, Shin D, Ding H, Weng HL. Follistatin-controlled activin-HNF4α-coagulation factor axis in liver progenitor cells determines outcome of acute liver failure. Hepatology. 2022;75:322-337.

    8. Colucci S, Altamura S, Marques O, Dropmann A, Horvat NK, Müdder K, Hammad S, Dooley S, Muckenthaler MU. Liver Sinusoidal Endothelial Cells Suppress Bone Morphogenetic Protein 2 Production in Response to TGFβ Pathway Activation. Hepatology. 2021;74:2186-2200.

    9. Dropmann A*, Dooley S*#, Dewidar B, Hammad S, Dediulia T, Werle J, Hartwig V, Ghafoory S, Woelfl S, Korhonen H, Janicot M, Wosikowski K, Itzel T, Teufel A, Schuppan D, Stojanovic A, Cerwenka A, Nittka S, Piiper A, Gaiser T, Beraza N, Milkiewicz M, Milkiewicz P, Brain JG, Jones DEJ, Weiss TS, Zanger UM, Ebert M, Meindl-Beinker# NM. TGF-β2 silencing to target biliary-derived liver diseases. Gut. 2020;69:1677-1690.

    10. Fan W, Liu T, Chen W, Hammad S, Longerich T, Fu Y, Li N, He Y, Liu C, Zhang Y, Lian Q, Zhao X, Yan C, Li L, Yi C, Ling Z, Ma L, Zhao X, Xu H, Wang P, Cong M, You H, Liu Z, Wang Y, Chen J, Li D, Hui L, Dooley S*, Hou J, Jia J, Sun B. ECM1 Prevents Activation of Transforming Growth Factor beta, Hepatic Stellate Cells, and Fibrogenesis in Mice. Gastroenterology. 2019;157:1352-1367.

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